Azithromycin Versus Doxycycline for the Treatment of Genital Chlamydia Infection: A Meta-analysis of Randomized Controlled Trials
FYS Kong, SN Tabrizi, M Law, LA Vodstrcil, M Chen, CK Fairley, R Guy, C Bradshaw, JS Hocking
CLINICAL INFECTIOUS DISEASES | OXFORD UNIV PRESS INC | Published : 2014
BACKGROUND: There has been recent debate questioning the efficacy of azithromycin for the treatment of urogenital chlamydia infection. We conducted a meta-analysis to compare the efficacy of 1 g azithromycin with 100 mg doxycycline twice daily (7 days) for the treatment of urogenital chlamydia infection. METHODS: Medline, PubMed, Embase, Cochrane Controlled Trials Register, Cochrane reviews, and Cumulative Index to Nursing and Allied Health Literature were searched until 31 December 2013. Randomized controlled trials comparing azithromycin with doxycycline for the treatment of genital chlamydia with evaluation of microbiological cure within 3 months of treatment were included. Sex, diagnosti..View full abstract
Awarded by National Health and Medical Research Council
Financial support. This work was supported by an Australian Postgraduate Award for F. Y. S. K. and the National Health and Medical Research Council (APP1042907 for J. S. H.).