Journal article

Gastrointestinal Dysmotility in Rett Syndrome

Gordon Baikie, Madhur Ravikumara, Jenny Downs, Nusrat Naseem, Kingsley Wong, Alan Percy, Jane Lane, Batia Weiss, Carolyn Ellaway, Katherine Bathgate, Helen Leonard

Journal of Pediatric Gastroenterology and Nutrition | LIPPINCOTT WILLIAMS & WILKINS | Published : 2014

Abstract

OBJECTIVES: Through evidence review and the consensus of an expert panel, we developed recommendations for the clinical management of gastroesophageal reflux disease, constipation, and abdominal bloating in Rett syndrome. METHODS: Based on review of the literature and family concerns expressed on RettNet, initial draft recommendations were created. Wherein the literature was lacking, 25 open-ended questions were included. Input from an international, multidisciplinary panel of clinicians was sought using a 2-stage modified Delphi process to reach consensus agreement. Items related to the clinical assessment and management of gastroesophageal reflux disease, constipation, and abdominal bloati..

View full abstract

Grants

Awarded by National Institutes of Health


Awarded by National Medical and Health Research Council (NHMRC)


Awarded by NHMRC Senior Research Fellowship


Awarded by NIH (NCRR grant)


Awarded by NATIONAL CENTER FOR RESEARCH RESOURCES


Funding Acknowledgements

Funding for this project was provided by the Rett Syndrome Association UK. The Australian Rett Syndrome program was funded by the National Institutes of Health (5R01HD043100-05) and the National Medical and Health Research Council (NHMRC; project grant nos 303189 and 1004384) for certain clinical aspects. The international Rett syndrome research program was funded by the International Rett Syndrome Foundation.H.L. received funding from an NHMRC Senior Research Fellowship (grant no 572568). A.P. and J.L. received research support from NIH (NCRR grant no U54 RR019478 and U54 HD06122) and the International Rett Syndrome Foundation.