Journal article

Structural studies of the resistance of influenza virus neuramindase to inhibitors

BJ Smith, JL McKimm-Breshkin, M McDonald, RT Fernley, JN Varghese, PM Colman

Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2002

DOI: 10.1021/jm010528u

University of Melbourne Researchers

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Keywords

Models, Molecular
Potent
Sialidase
Protein Binding
Cyclopentanes
Science & Technology
Acid
Zanamivir
Pharmacology & Pharmacy
Sensitivity
Crystallography, X-Ray
Guanidines
Sialic Acids
Antiviral Agents
Mutation
Complex
Chemistry, Medicinal
Enzyme Inhibitors
Models
Acetamides
Variant
Drug Design
Acids, Carbocyclic
Influenzavirus a
Neuraminidase
Pyrans
Oseltamivir
Neuraminidase Inhibitor
Drug Resistance, Viral
Life Sciences & Biomedicine