Short Report: Pyrethroid Susceptibility in Natural Populations of the Anopheles punctulatus Group (Diptera: Culicidae) in Papua New Guinea
John B Keven, Cara N Henry-Halldin, Edward K Thomsen, Ivo Mueller, Peter M Siba, Peter A Zimmerman, Lisa J Reimer
American Journal of Tropical Medicine and Hygiene | AMER SOC TROP MED & HYGIENE | Published : 2010
The development of insecticide resistance has compromised mosquito control efforts in many parts of the world. Papua New Guinea (PNG) has a long history of dichlorodiphenyltrichloroethane (DDT) use and currently distributes pyrethroid-treated nets for malaria control. This study is the first to investigate the status of pyrethroid resistance in the Anopheles punctulatus group, the major malaria and filariasis vectors of PNG. The study used World Health Organization standard susceptibility bioassays to detect knockdown phenotypes and a novel nested polymerase chain reaction to detect the knockdown resistant (kdr) allele in these vectors. Our results show 100% susceptibility to pyrethroids in ..View full abstract
Awarded by US National Institute of Health
Awarded by FOGARTY INTERNATIONAL CENTER
This study was supported by Rotary Against Malaria, Fogarty International Centre, and the US National Institute of Health (Grants TW007377 and TW007872).