A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010
Peter W Gething, Iqbal RF Elyazar, Catherine L Moyes, David L Smith, Katherine E Battle, Carlos A Guerra, Anand P Patil, Andrew J Tatem, Rosalind E Howes, Monica F Myers, Dylan B George, Peter Horby, Heiman FL Wertheim, Ric N Price, Ivo Mueeller, Kevin Baird, Simon I Hay
PLoS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2012
BACKGROUND: Current understanding of the spatial epidemiology and geographical distribution of Plasmodium vivax is far less developed than that for P. falciparum, representing a barrier to rational strategies for control and elimination. Here we present the first systematic effort to map the global endemicity of this hitherto neglected parasite. METHODOLOGY AND FINDINGS: We first updated to the year 2010 our earlier estimate of the geographical limits of P. vivax transmission. Within areas of stable transmission, an assembly of 9,970 geopositioned P. vivax parasite rate (PvPR) surveys collected from 1985 to 2010 were used with a spatiotemporal Bayesian model-based geostatistical approach to ..View full abstract
Awarded by Wellcome Trust
Awarded by Bill and Melinda Gates Foundation
SIH is funded by a Senior Research Fellowship from the Wellcome Trust (#095066), which also supports PWG, CAG, and KEB. CLM and APP are funded by a Biomedical Resources Grant from the Wellcome Trust (#091835). REH is funded by a Biomedical Resources Grant from the Wellcome Trust (#085406). IRFE is funded by grants from the University of Oxford-Li Ka Shing Foundation Global Health Program and the Oxford Tropical Network. DLS and AJT are supported by grants from the Bill and Melinda Gates Foundation (#49446, #1032350) (http://www.gatesfoundation.org). PH is supported by Wellcome Trust grants 089276/Z/09/Z and the Li Ka Shing Foundation. RNP is a Wellcome Trust Senior Fellow in Clinical Science (#091625). JKB is supported by a Wellcome Trust grant (#B9RJIXO). PWG, APP, DLS, AJT, DBG, and SIH also acknowledge support from the RAPIDD program of the Science and Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health (http://www.fic.nih.gov). This work forms part of the output of the Malaria Atlas Project (MAP, http://www.map.ox.ac.uk), principally funded by the Wellcome Trust, UK (http://www.wellcome.ac.uk). MAP also acknowledges the support of the Global Fund to Fight AIDS, Tuberculosis, and Malaria (http://www.theglobalfund.org). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.