Journal article

Suboptimal management of unfractionated heparin compared with low-molecular- weight heparin in the management of pulmonary embolism

YH Khor, R Smith, CF McDonald

Internal Medicine Journal | WILEY | Published : 2014

Abstract

BACKGROUND: Both low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) have been shown to be equivalent in efficacy and safety profiles for the management of pulmonary embolism (PE). AIMS: To assess the real world management of anticoagulation in PE in a tertiary hospital setting. METHODS: An audit of patients with a new diagnosis of PE from March 2011 to March 2012. Data collected included patient demographics, anticoagulant, complication, mortality, time to first administration, frequency of monitoring and dose adjustment for UFH, time to therapeutic range for UFH (based on activated partial thromboplastin time) and length of hospital stay. RESULTS: Of the 211 patients who w..

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