The effect of positive expiratory pressure (PEP) therapy on symptoms, quality of life and incidence of re-exacerbation in patients with acute exacerbations of chronic obstructive pulmonary disease: a multicentre, randomised controlled trial
Christian R Osadnik, Christine F McDonald, Belinda R Miller, Catherine J Hill, Ben Tarrant, Ranjana Steward, Caroline Chao, Nicole Stodden, Cristino C Oliveira, Nadia Gagliardi, Anne E Holland
Thorax | BMJ PUBLISHING GROUP | Published : 2014
BACKGROUND: Positive expiratory pressure (PEP) is a technique used to enhance sputum clearance during acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The impact of PEP therapy during acute exacerbations on clinically important outcomes is not clear. This study sought to determine the effect of PEP therapy on symptoms, quality of life and future exacerbations in patients with AECOPD. METHODS: 90 inpatients (58 men; mean age 68.6 years, FEV(1) 40.8% predicted) with AECOPD and sputum expectoration were randomised to receive usual care (including physical exercise)±PEP therapy. The Breathlessness, Cough and Sputum Scale (BCSS), St George's Respiratory Questionnaire (SGRQ) ..View full abstract
Awarded by Australian Physiotherapy Association Physiotherapy Research Foundation
CO received a La Trobe University Postgraduate Scholarship and grants from the Australian Physiotherapy Association Physiotherapy Research Foundation (S10-010), the Institute for Breathing and Sleep, and La Trobe University.