The Combination of Colistin and Doripenem Is Synergistic against Klebsiella pneumoniae at Multiple Inocula and Suppresses Colistin Resistance in an In Vitro Pharmacokinetic/Pharmacodynamic Model
Zakuan Z Deris, Heidi H Yu, Kathryn Davis, Rachel L Soon, Jovan Jacob, Caron K Ku, Anima Poudyal, Phillip J Bergen, Brian T Tsuji, Jurgen B Bulitta, Alan Forrest, David L Paterson, Tony Velkov, Jian Li, Roger L Nation
Antimicrobial Agents and Chemotherapy | AMER SOC MICROBIOLOGY | Published : 2012
Awarded by National Institute of Allergy and Infectious Diseases (NIAID)
The study was supported by R01AI079330 and R01AI070896 from the National Institute of Allergy and Infectious Diseases (NIAID). T. V., R.L.N., and J.L. are supported by the Australian National Health and Medical Research Council (NHMRC). J.L. is an Australian NHMRC senior research fellow. T. V. is an Australian NHMRC Industry Career Development research fellow. J.B.B. is supported by an Australian Research Council (ARC) DECRA fellowship. Z.Z.D. is a Ph.D. candidate cosponsored by the Malaysian government and Universiti Sains Malaysia.