Journal article

Hatching time for monotreme immunology

Emily SW Wong, Anthony T Papenfuss, Robert D Miller, Katherine Belov

Australian Journal of Zoology | CSIRO PUBLISHING | Published : 2009

Abstract

The sequencing of the platypus genome has spurred investigations into the characterisation of the monotreme immune response. As the most divergent of extant mammals, the characterisation of the monotreme immune repertoire allows us to trace the evolutionary history of immunity in mammals and provide insights into the immune gene complement of ancestral mammals. The immune system of monotremes has remained largely uncharacterised due to the lack of specific immunological reagents and limited access to animals for experimentation. Early immunological studies focussed on the anatomy and physiology of the lymphoid system in the platypus. More recent molecular studies have focussed on characteris..

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University of Melbourne Researchers