Journal article

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

Isabella Pacchiarotti, David J Bond, Ross J Baldessarini, Willem A Nolen, Heinz Grunze, Rasmus W Licht, Robert M Post, Michael Berk, Guy M Goodwin, Gary S Sachs, Leonardo Tondo, Robert L Findling, Eric A Youngstrom, Mauricio Tohen, Juan Undurraga, Ana Gonzalez-Pinto, Joseph F Goldberg, Aysegul Yildiz, Lori L Altshuler, Joseph R Calabrese Show all

American Journal of Psychiatry | AMER PSYCHIATRIC PUBLISHING, INC | Published : 2013

University of Melbourne Researchers

Grants

Funding Acknowledgements

Dr. Bond has received honoraria from the Canadian Network for Mood and Anxiety Treatments, the Canadian Psychiatric Association, Pfizer, Sunovion, Bristol-Myers Squibb, Otsuka, AstraZeneca, and Janssen-Ortho; and has received research grants from the Canadian Institutes of Health Research, the UBC Institute of Mental Health/Coast Capital Depression Research Fund, and Pfizer. Dr. Nolen has received grants from the Netherlands Organization for Health Research and Development, the European Union, the Stanley Medical Research Institute, AstraZeneca, GlaxoSmithKline, and Wyeth and honoraria or speaking fees from AstraZeneca and Lundbeck. Dr. Grunze has received research support, consulting fees, or honoraria from AstraZeneca, Bristol-Myers Squibb, Desitin, Eli Lilly, Gedeon-Richter, Hoffmann-La Roche, Janssen-Cilag, Lundbeck, Merck, Otsuka, Sanofi-Aventis, Servier, Sepracor, and UBC. Dr. Licht has served on advisory boards for Bristol-Myers Squibb, AstraZeneca, and MSD and has received honoraria from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen-Cilag, Lundbeck, and Pfizer. Dr. Post has served as a consultant or speaker for AstraZeneca, Sunovion, Teva, and Validas. Dr. Berk has received research support from or served as a consultant or speaker for AstraZeneca, Beyond Blue, Bristol-Myers Squibb, Cancer Council of Victoria, Cooperative Research Centre, Eli Lilly, Geelong Medical Research Foundation, GlaxoSmithKline, Janssen Cilag, Lundbeck, Mayne Pharma, MBF, Meat and Livestock Board, Merck, National Health and Medical Research Council (Australia), NIH, Novartis, Organon, Pfizer, Rotary Health, Sanofi Synthelabo, Servier, Simons Autism Foundation, Stanley Medical Research Foundation, Solvay, Woolworths, and Wyeth and is a co-inventor on two provisional patents regarding the use of N-acetylcysteine and related compounds for psychiatric indications. Dr. Goodwin has received grants from Bailly Thomas, Medical Research Council, National Institute for Health Research (U.K.), and Servier, has served as consultant, adviser, or CME speaker for AstraZeneca, Bristol-Myers Squibb, Boehringer Ingelheim, Cephalon/Teva Janssen-Cilag, Eli Lilly, Lundbeck, Otsuka, P1Vital, Roche, Servier, Schering-Plough, Shire, Sunovion, and Takeda, and holds shares in P1Vital. Dr. Sachs has served on advisory boards for Elan, Janssen, Merck, Otsuka, Roche, Sunovion, and Takeda. Dr. Findling has received research support or served as a consultant or speaker for Alexza Pharmaceuticals, American Psychiatric Publishing, AstraZeneca, Bracket, Bristol-Myers Squibb, Clinsys, Cognition Group, Forest, GlaxoSmithKline, Guilford Press, Johns Hopkins University Press, Johnson & Johnson, KemPharm, Lilly, Lundbeck, Merck, NIH, Novartis, Noven, Otsuka, Oxford University Press, Pfizer, Physicians Postgraduate Press, Rhodes Pharmaceuticals, Roche, Sage, Seaside Pharmaceuticals, Shire, Stanley Medical Research Institute, Sunovion, Supernus Pharmaceuticals, Transcept Pharmaceuticals, Validus, and WebMD. Dr. Youngstrom has served as a consultant for Lundbeck. Dr. Tohen has received honoraria from or served as a consultant for AstraZeneca, Bristol-Myers Squibb, Elan, Eli Lilly, Forest, GlaxoSmithKline, Johnson & Johnson, Lundbeck, Merck, Otsuka, PamLab, Roche, Sunovion, Teva, Wyeth, and Wiley Publishing; his spouse is an employee and stockholder at Eli Lilly. Dr.Gonzalez-Pinto has received grants from or served as consultant, adviser, or CME speaker for Almirall, AstraZeneca, Bristol-Myers Squibb, Cephalon, Eli Lilly, GlaxoSmithKline, Janssen-Cilag, Jazz, Johnson & Johnson, Lundbeck, Merck, Otsuka, Pfizer, Sanofi-Aventis, Servier, Schering-Plough, Solvay, the Spanish Ministry of Science and Innovation (CIBERSAM), the Ministry of Science (Carlos III Institute), the Basque Government, Stanley Medical Research Institute, and Wyeth. Dr. Goldberg has served as consultant or speaker for AstraZeneca, Grunenthal Group, Medscape, Merck, Mylan Pharmaceuticals, Novartis, Sunovion, and WebMD and receives royalties from American Psychiatric Publishing. Dr. Yildiz has received research grants from or served as a consultant or speaker for Abdi Ibrahim, Actavis, Ali Raif, AstraZeneca, Bristol-Myers Squibb, Janssen-Cilag, Lundbeck, Pfizer, Sanofi-Aventis, and Servier. Dr. Altshuler has served on advisory boards or as a consultant for Eli Lilly, Takeda Pharmaceuticals North America, Lundbeck, Sepracor, and Sunovion. Dr. Calabrese has received funding or research support from or served as a consultant or CME speaker or on advisory boards for Abbott, AstraZeneca, Bristol-Myers Squibb, Cephalon, Cleveland Foundation, Dainippon Sumitomo, Department of Defense, Eli Lilly, EPI-Q, Forest, France Foundation, GlaxoSmithKline, Health Resources Services Administration, Janssen, Johnson & Johnson, Lundbeck, Merck, NARSAD, Neurosearch, NIMH, Ortho-McNeil, Otsuka, Pfizer, Repligen, Sanofi-Aventis, Schering-Plough, Servier, Solvay, Stanley Medical Research Institute, Supernus, Synosia, Takeda, and Wyeth. Dr. Thase has received grant funding from or served as a consultant for Agency for Healthcare Research and Quality, Alkermes, Allergan, AstraZeneca, Bristol-Myers Squibb, Dey Pharma, Eli Lilly, Forest Laboratories, Forest Pharmaceuticals, Gerson Lehman Group, GlaxoSmithKline, Guidepoint Global, Lundbeck, MedAvante, Merck, NeoSync, Neuronetics, NIMH, Novartis, Otsuka, Ortho-McNeil Pharmaceuticals, PamLab, Pfizer (formerly Wyeth-Ayerst Laboratories), PharmaNeuroboost, Roche Laboratories, Shire US, Sunovion, Takeda, Teva, and Transcept; he receives royalties from American Psychiatric Foundation, Guilford Publications, Herald House, Oxford University Press, and W. W. Norton and has equity holdings in MedAvante; his wife is employed by Peloton Advantage, which does business with Pfizer. Dr. Colom has served as adviser or speaker for Adamed, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Lundbeck, MSD-Merck, Otsuka, Pfizer, Sanofi-Aventis, Shire, and Tecnifar and has received copyright fees from Cambridge University Press, Igaku-Shoin, Solal Ed., Ars Medica, Giovani Fioriti Ed., Medipage, La Esfera de Los Libros, Morales i Torres Ed, Panamericana, and Mayo Ed. & Columna. Dr. Frye has received grant support from the Mayo Foundation, Myriad, NARSAD, the National Institute of Alcohol Abuse and Alcoholism, NIMH, and Pfizer and travel support from Advanced Health Media, AstraZeneca, Bristol-Myers Squibb, Chilean Society of Neurology, Psychiatry, and Neurosurgery, Colombian Society of Neuropsychopharmacology, GlaxoSmithKline, Otsuka, and Sanofi-Aventis; he has served as an unpaid consultant for Allergan, Merck, Myriad, Sanofi-Aventis, Sunovion, Takeda Global Research, Teva Pharmaceuticals, and United Biosource Corporation. Dr. Malhi has received research support from or served as a speaker or consultant for AstraZeneca, Eli Lilly, Janssen-Cilag, Lundbeck, Organon, Pfizer, Ranbaxy, Servier, and Wyeth. Dr.Fountoulakis has received research support or travel support from or served as a speaker or consultant for AstraZeneca, Bristol-Myers Squibb, Janssen-Cilag, Eli Lilly, Pfizer Foundation, and Wyeth. Dr. Vazquez has served as consultant or speaker for AstraZeneca, Gador, GlaxoSmithKline, Ivax, Eli Lilly, Lundbeck, Pfizer, Raffo, Servier, and Novartis. Dr. Perlis has served on advisory boards or as a consultant for Genomind, Healthrageous, PamLab, Pfizer, Proteus Biomedical, and RIDVentures. Dr. Ketter has received research support from or served as a consultant or speaker for Abbott, Allergan, AstraZeneca, Avanir, Bristol-Myers Squibb, Cephalon, Eli Lilly, Forest Pharmaceuticals, GlaxoSmithKline, Janssen, Merck, Otsuka, Pfizer, Sunovion, and Teva; he receives royalties from American Psychiatric Publishing, and his spouse is an employee of and holds stock in Janssen Pharmaceuticals. Dr. Akiskal receives honoraria or fees from Journal of Affective Disorders, AstraZeneca, University of Lisbon, Aristotle University of Thesaloniki, Sanofi, Nevada Psychiatric Association, and Medical Education Speakers Network. Dr. Azorin has received grants from Eli Lilly and Sanofi and honoraria from AstraZeneca, Bristol-Myers Squibb, Lundbeck Servier, and Eli Lilly; he has served on advisory boards for Eli Lilly, Lundbeck, Bristol-Myers Squibb, and Roche and as an expert witness for Eli Lilly. Dr. Lafer has received grant or research support from Brazilian research agencies CAPES (Coordination for the Improvement of Higher Education Personnel), FAPESP (Sao Paulo Research Foundation), and CNPq (National Council for Scientific and Technological Development). Dr. Kato has received research support from Takeda and honoraria for lectures, manuscripts, or consultancy from Kyowa Hakko Kirin, Eli Lilly Japan, Otsuka, GlaxoSmithKline, Taisho Toyama Pharmaceutical, Dainippon Sumitomo, Meiji Seika Pharma, Pfizer Japan, Mochida Pharmaceutical, Shionogi, Janssen, and Astellas. Dr. Martinez-Aran has served as speaker or adviser for Bristol-Myers Squibb, Lundbeck, Otsuka, and Pfizer. Dr. Parker has served as a speaker or on advisory boards for or received travel or speaking fees from AstraZeneca, Eli Lilly, Lundbeck, Pfizer, and Servier. Dr. Souery has served on advisory boards for AstraZeneca and Lundbeck and has received unrestricted grants for clinical research and educational activities from AstraZeneca, GlaxoSmithKline, and Lundbeck. Dr. Ozerdem has received honoraria or travel support from Abdi Ibrahim, Adeka, AstraZeneca, Bristol-Myers Squibb, EGIS, GlaxoSmithKline, Lundbeck, Nobel, Pfizer, Schering-Plough, and Servier. Dr. McElroy has served as a consultant for or on scientific advisory boards for Alkermes, Bracket, Corcept, MedAvante, Shire, Sunovion, and Teva; she is a principal or co-investigator on studies sponsored by the Agency for Healthcare Research and Quality, Alkermes, AstraZeneca, Cephalon, Eli Lilly, Forest, Marriott Foundation, NIMH, Orexigen Therapeutics, Pfizer, Shire, Takeda, and Transcept; she is also an inventor on a patent for use of sulfamate derivatives for treating impulse control disorders. Dr. Girardi has received research support from, served on advisory boards for, and received honoraria from Eli Lilly, Janssen, Otsuka, Pfizer, Schering, and Springer Healthcare. Dr.Bauer has received research support from or served as a consultant or speaker for Alkermes, American Foundation for Suicide Prevention, AstraZeneca, Bristol-Myers Squibb, Bundesministerium fur Bildung und Forschung, Deutsche Forschungsgemeinschaft, European Commission (FP7), Ferrer Internacional, GlaxoSmithKline, Janssen, Eli Lilly, Lundbeck, NARSAD, Otsuka, Pfizer, Servier, Stanley Medical Research Institute, and Takeda. Dr. Yatham has received research support from or served as a speaker or advisory board member for AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, GlaxoSmithKline, Lundbeck, Novartis, Pfizer, Servier, and Sunovion. Dr. Zarate is listed as a co-inventor on a patent application for the use of ketamine and its metabolites in major depression. Dr. Nierenberg has received research support from, served as a consultant for, or received honoraria from Abbott Laboratories, Agency for Healthcare Research and Quality, American Drug Utilization Review Society, American Society for Clinical Psychopharmacology, AstraZeneca, Basilea, Biomedical Development, Boston Center for the Arts, BrainCells, Brandeis University, Bristol-Myers Squibb, Cederroth, Cephalon, Corcept, Cyberonics, East Asian Bipolar Forum, Elan, Eli Lilly, Forest, Genaissance, GlaxoSmithKline, Harold Grinspoon Charitable Foundation, Health New England, Innapharma, International Society for Bipolar Disorder, Janssen, Jazz Pharmaceuticals, Lichtwer Pharma, Lundbeck, Merck, MGH Psychiatry Academy, Mid-Atlantic Permanente Research Institute, Mylan (formerly Dey Pharmaceuticals), NARSAD, NIMH, Novartis, PamLab, Pfizer, PGx Health, Ridge Diagnostics, Roche, Sepracor, Schering-Plough, Shire, Somerset, Stanley Foundation, Sunovion, Takeda, Targacept, Teva, University of Pisa, University of Wisconsin at Madison, University of Texas Southwestern Medical Center at Dallas, Wyeth-Ayerst, and Zucker Hillside Hospital; he receives other income from legal case reviews for CRICO, MBL Publishing for past services as editor-in-chief of CNS Spectrums, Slack Inc. for services as associate editor of Psychiatric Annals, and from Belvoir Publications for serving on the editorial board of Mind, Mood, and Memory; he has copyright joint ownership with MGH for the Structured Clinical Interview for MADRS and Clinical Positive Affect Scale and is a stakeholder in Appliance Computing (MindSite), Brain Cells, and InfoMed. Dr. Birmaher has received research support from NIMH and royalties from Random House, Lippincott Williams & Wilkins, and UpToDate. Dr. Kanba has received research support or honoraria from Astellas, Dainippon Sumitomo, Eisai, Eli Lilly Japan, GlaxoSmithKline, Janssen, Kyowa Hakko Kirin, Meiji Seika Pharma, MSD, Ono, Otsuka, Pfizer, Shionogi, Taisho Toyama, Wyeth, and Yoshitomiyakuhin. Dr. El-Mallakh has received research support from Merck and has served as a speaker for AstraZeneca and Otsuka. Dr. Serretti has served as a consultant or speaker for Abbott, Angelini, AstraZeneca, Bristol-Myers Squibb, Boehringer, Clinical Data, Eli Lilly, GlaxoSmithKline, Italfarmaco, Janssen, Lundbeck, Pfizer, Sanofi, and Servier. Dr. MacQueen has received research support from AstraZeneca and served as a consultant or speaker for Bristol-Myers Squibb, Canadian Psychiatric Association, Eli Lilly, Lundbeck, Norlien Foundation, Pfizer, Sanofi, and Servier. Dr. Bowden has received grant support from Novartis. Dr. Ghaemi has received research support from Takeda and has served as a consultant for Sunovion. Dr.Lopez-Jaramillo has received research support from Janssen Cilag, Lundbeck, NIH, Novartis, Pfizer, and University of Antioquia and honoraria from Abbott, GlaxoSmithKline, Eli Lilly, Lundbeck, Pfizer, Sanofi, and Servier. Dr. Ha has received research support or honoraria from AstraZeneca, Eli Lilly, Pfizer, and Otsuka. Dr. Perugi has received research support from or served as a consultant, speaker, or advisory board member for AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen-Cilag, Lundbeck, and Sanofi-Aventis. Dr. Kasper has received research support from or served as a consultant, speaker, or advisory board member for Angelini, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen, Lundbeck, MSD, Neuraxpharm, Novartis, Organon, Pfizer, Pierre Fabre, Schwabe, Sepracor, and Servier. Dr. Hirschfeld has served as a consultant for or received honoraria from American College of Psychiatrists, Biostrategies, Brown University, CME Alliance, CME Outfitters, Equinox Group, Grey Healthcare, Letters & Sciences, Merck Manual Editorial Board, Nevada Psychiatric Association, and Physicians Post Graduate Press Health and Wellness Partners and receives royalties from Jones & Bartlett and Taylor & Francis. Dr. Kapczinski has received research support from or served as a consultant or speaker for AstraZeneca, CNPq, CAPES, Eli Lilly, Janssen, Janssen-Cilag, NARSAD, Stanley Medical Research Institute, and Servier. Dr. Vieta has received research support from or served as consultant, adviser, or speaker for Alexza, Almirall, AstraZeneca, Bristol-Myers Squibb, Elan, Eli Lilly, Ferrer, Forest Research Institute, 7th Framework Program of the European Union, Geodon Richter, GlaxoSmithKline, Janssen-Cilag, Jazz, Lundbeck, Merck, Novartis, Organon, Otsuka, Pfizer, Roche, Sanofi-Aventis, Servier, Solvay, Schering-Plough, Shire, Spanish Ministry of Science and Innovation, Stanley Medical Research Institute, Takeda, Teva, United Biosource Corporation, and Wyeth. The remaining authors report no competing interests.