Journal article
Enhancing DNA vaccines
AM Lew, JL Brady, CM Dyer, B McKenzie, AJ Kelly, JS Boyle
Immunologist | HOGREFE & HUBER PUBLISHERS | Published : 2000
Abstract
DNA vaccines represent an exciting new method of stimulating immune responses. However, to date their efficacy had been poor. Here, Andrew M. Lew and coworkers show that by manipulation of the site of immunization, antigen expression, and targeting of the antigen to cells of the immune system, the response can be enhanced.