The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
Rachael Keating, Tomer Hertz, Marie Wehenkel, Tarsha L Harris, Benjamin A Edwards, Jennifer L McClaren, Scott A Brown, Sherri Surman, Zachary S Wilson, Philip Bradley, Julia Hurwitz, Hongbo Chi, Peter C Doherty, Paul G Thomas, Maureen A McGargill
Nature Immunology | NATURE PUBLISHING GROUP | Published : 2013
Awarded by National Institute of Allergy and Infectious Diseases of the US National Institutes of Health, Department of Health and Human Services
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
We thank H. Zeng (St. Jude Children's Research Hospital) for mice with inducible deletion of Rptor in B cells; B. Creasy and T. Oguin for technical support; P. Vogel and the Veterinary Pathology Core at St. Jude for histology; and S. Patrick and the staff of the Shared Animal Resource Center at St. Jude Children's Research Hospital for animal husbandry. Supported by the National Institute of Allergy and Infectious Diseases of the US National Institutes of Health, Department of Health and Human Services (HHSN266200700005C) and American Lebanese Syrian Associated Charities.