Journal article

The murine orthologue of human antichymotrypsin - A structural paradigm for CLADE A3 serpins

AJ Horvath, JA Irving, J Rossjohn, RH Law, SP Bottomley, NS Quinsey, RN Pike, PB Coughlin, JC Whisstock

JOURNAL OF BIOLOGICAL CHEMISTRY | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2005

DOI: 10.1074/jbc.M505598200

University of Melbourne Researchers

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Keywords

Temperature
Models, Molecular
Salts
Leukocytes
Alpha-1-Antichymotrypsin Polymorphism
Antithrombin
Humans
Likelihood Functions
Science & Technology
Mechanism
Association
Molecular Sequence Data
Alpha(1)-Antichymotrypsin
Alpha(1)-Proteinase Inhibitor
Electron-Density Maps
Mice
Identification
Biochemistry & Molecular Biology
Reactive Loop
Protein Structure, Tertiary
Evolution, Molecular
Molecular Conformation
Cathepsin-G
Codon
Protease Inhibitor
Threonine
Amino Acid Sequence
Serpins
Crystallography, X-Ray
Ligands
Dna-Binding
Animals
Inflammation
Protein Conformation
Sequence Homology, Amino Acid
Time Factors
Phylogeny
Trypsin
Protein Structure, Secondary
Alzheimers-Disease
Lung-Disease
Brain
Multiple Sequence Alignments
Kinetics
Life Sciences & Biomedicine
Circular Dichroism
Recombinant Proteins
Human Alpha-1-Antichymotrypsin
Leukocyte Elastase