Microcomputer analysis techniques for evaluation of benzodiazepine effects on rat electrocorticogram

Abstract

Quantitative analysis of drug effects on the EEG is usually performed on a minicomputer using an EEG signal that has been recorded on a high frequency FM tape recorded and edited to remove artefact. However, this equipment is expensive and so the present study evaluated a much cheaper system, an 'on-line' microcomputer and 3 programs for data reduction. Using this system to assess diazepam effects on the rat electrocorticogram, it was concluded that period amplitude analysis may be preferable to the Fast Fourier Transform or Hjorth analysis. © 1987.