Journal article

Influence of experience and qualification on PET-based target volume delineation When there is no expert-ask your colleague

C Doll, V Duncker-Rohr, G Ruecker, M Mix, M MacManus, D De Ruysscher, W Vogel, JG Eriksen, W Oyen, A-L Grosu, W Weber, U Nestle

Strahlentherapie und Onkologie | URBAN & VOGEL | Published : 2014

Abstract

BACKGROUND AND PURPOSE: The integration of positron emission tomography (PET) information for target volume delineation in radiation treatment planning is routine in many centers. In contrast to automatic contouring, research on visual-manual delineation is scarce. The present study investigates the dependency of manual delineation on experience and qualification. PATIENTS AND METHODS: A total of 44 international interdisciplinary observers each defined a [(18)F]fluorodeoxyglucose (FDG)-PET based gross tumor volume (GTV) using the same PET/CT scan from a patient with lung cancer. The observers were "experts" (E; n = 3), "experienced interdisciplinary pairs" (EP; 9 teams of radiation oncologi..

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Funding Acknowledgements

The authors thank the patient for agreement to use his image data and all participants of this contouring exercise, namely the participants of the ESTRO-EANM and the DEGRO Akademie teaching courses and the Freiburg colleagues, for allowing us to analyze their contours. We thank ESTRO, EANM, and DEGRO for permitting this kind of research in the context of their teaching courses. We especially thank David Gibon and his team from Aquilab for their helpful collaboration in the transfer and technical evaluation of the contours. We furthermore thank Scott Kaylor from Educase for transmitting the html contour files from FALCON for further evaluation and Christine Verfaille from ESTRO for her help herewith. This work would not have been possible without the assistance of the staff of the Departments of Radiation Oncology and Nuclear Medicine of the University Medical Center Freiburg. This study was supported by the Radiation Oncology Department of the University Medical Center Freiburg.