Conference Proceedings

Distributed BLAST in a grid computing context

MM Bayer, R Sinnott, MR Berthold (ed.), R Glen (ed.), K Diederichs (ed.), O Kohlbacher (ed.), I Fischer (ed.)

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | SPRINGER-VERLAG BERLIN | Published : 2005

Abstract

The Basic Local Alignment Search Tool (BLAST) is one of the best known sequence comparison programs available in bioinformatics. It is used to compare query sequences to a set of target sequences, with the intention of finding similar sequences in the target set. Here, we present a distributed BLAST service which operates over a set of heterogeneous Grid resources and is made available through a Globus toolkit v.3 Grid service. This work has been carried out in the context of the BRIDGES project, a UK e-Science project aimed at providing a Grid based environment for biomedical research. Input consisting of multiple query sequences is partitioned into sub-jobs on the basis of the number of id..

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