Journal article

Postnatal corticosteroids in preterm infants: Systematic review of effects on mortality and motor function

LW Doyle, PG Davis

Journal of Paediatrics and Child Health | BLACKWELL SCIENCE ASIA | Published : 2000

Abstract

BACKGROUND: Postnatal corticosteroid therapy has been proved in randomized controlled trials to reduce ventilator dependence and the rate of chronic lung disease in preterm infants with few serious short-term side effects. However, there are other consequences that might follow postnatal corticosteroid therapy that are more important, including mortality or cerebral palsy. OBJECTIVES: To review the evidence from reported randomized controlled trials on the effects of postnatal corticosteroid on long-term mortality and motor dysfunction, including cerebral palsy. METHODS: The methods involved a meta-analysis of reported randomized controlled trials, following guidelines of the Cochrane Collab..

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