Journal article

Location and Pathogenic Potential of Blastocystis in the Porcine Intestine

Wenqi Wang, Helle Bielefeldt-Ohmann, Rebecca J Traub, Leigh Cuttell, Helen Owen

PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2014


Blastocystis is an ubiquitous, enteric protozoan of humans and many other species. Human infection has been associated with gastrointestinal disease such as irritable bowel syndrome, however, this remains unproven. A relevant animal model is needed to investigate the pathogenesis/pathogenicity of Blastocystis. We concluded previously that pigs are likely natural hosts of Blastocystis with a potentially zoonotic, host-adapted subtype (ST), ST5, and may make suitable animal models. In this study, we aimed to characterise the host-agent interaction of Blastocystis and the pig, including localising Blastocystis in porcine intestine using microscopy, PCR and histopathological examination of tissu..

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University of Melbourne Researchers


Awarded by University of Queensland

Funding Acknowledgements

Financial support for this project has been provided for by: 1) William Peter Richards Trust Award Grant (WW) and 2) The University of Queensland New Staff Start-up Grant, Research Master number: 2010000368 (HO). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.