Location and Pathogenic Potential of Blastocystis in the Porcine Intestine
Wenqi Wang, Helle Bielefeldt-Ohmann, Rebecca J Traub, Leigh Cuttell, Helen Owen
PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2014
Blastocystis is an ubiquitous, enteric protozoan of humans and many other species. Human infection has been associated with gastrointestinal disease such as irritable bowel syndrome, however, this remains unproven. A relevant animal model is needed to investigate the pathogenesis/pathogenicity of Blastocystis. We concluded previously that pigs are likely natural hosts of Blastocystis with a potentially zoonotic, host-adapted subtype (ST), ST5, and may make suitable animal models. In this study, we aimed to characterise the host-agent interaction of Blastocystis and the pig, including localising Blastocystis in porcine intestine using microscopy, PCR and histopathological examination of tissu..View full abstract
Awarded by University of Queensland
Financial support for this project has been provided for by: 1) William Peter Richards Trust Award Grant (WW) and 2) The University of Queensland New Staff Start-up Grant, Research Master number: 2010000368 (HO). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.