Myopia Is Associated With Lower Vitamin D Status in Young Adults
Seyhan Yazar, Alex W Hewitt, Lucinda J Black, Charlotte M McKnight, Jenny A Mountain, Justin C Sherwin, Wendy H Oddy, Minas T Coroneo, Robyn M Lucas, David A Mackey
Investigative Ophthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2014
PURPOSE: To investigate the association between serum vitamin D levels and myopia in young adults. METHODS: A total of 946 individuals participating in the 20-year follow-up of the Western Australian Pregnancy Cohort (Raine) Study were included in this study. Ethnicity, parental myopia, and education status were ascertained by self-reported questionnaire. A comprehensive ophthalmic examination was performed, including postcycloplegic autorefraction and conjunctival UV autofluorescence photography. Serum 25-hydroxyvitamin D₃ (25(OH)D₃) concentrations were determined using mass spectrometry. The association between serum 25(OH)D₃ concentrations and prevalent myopia was determined using multiva..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
Awarded by NHMRC
The core management of the Raine Study is funded by University of Western Australia; Telethon Kids Institute; Raine Medical Research Foundation; University of Western Australia Faculty of Medicine, Dentistry and Health Sciences; Women's and Infant's Research Foundation; and Curtin University. The 20-year eye follow-up of the Raine Study was funded by National Health and Medical Research Council (NHMRC) Grant 1021105, Ophthalmic Research Institute of Australia (ORIA), Lions Eye Institute, the Australian Foundation for the Prevention of Blindness, and Alcon Research Institute. NHMRC Project 1022134 (2012-2014) funded LB and the serum 25(OH) D assays that were conducted by RDDT in Melbourne, Victoria, Australia. RML and WHO are funded by NHMRC Career Development Fellowships. The Centre for Eye Research Australia receives operational infrastructure support from the Victorian Government.