Journal article

Dietary patterns and cognitive decline in an Australian study of ageing

SL Gardener, SR Rainey-Smith, MB Barnes, HR Sohrabi, M Weinborn, YY Lim, K Harrington, K Taddei, Y Gu, A Rembach, C Szoeke, KA Ellis, CL Masters, SL Macaulay, CC Rowe, D Ames, JB Keogh, N Scarmeas, RN Martins

Molecular Psychiatry | Nature Publishing Group | Published : 2015

Abstract

The aim of this paper was to investigate the association of three well-recognised dietary patterns with cognitive change over a 3-year period. Five hundred and twenty-seven healthy participants from the Australian Imaging, Biomarkers and Lifestyle study of ageing completed the Cancer Council of Victoria food frequency questionnaire at baseline and underwent a comprehensive neuropsychological assessment at baseline, 18 and 36 months follow-up. Individual neuropsychological test scores were used to construct composite scores for six cognitive domains and a global cognitive score. Based on self-reported consumption, scores for three dietary patterns, (1) Australian-style Mediterranean diet (Aus..

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Funding Acknowledgements

We acknowledge the contribution of Rosalind Miller (CSIRO) who developed the method of estimating the portion of fixed effect variance in linear mixed models. Samantha Gardener is supported by a University Postgraduate Award from the Dementia Collaborative Research Centres program. Funding for the study is provided by the CSIRO Flagship Collaboration Fund and the Science and Industry Endowment Fund (SIEF) in partnership with Edith Cowan University (ECU), The Florey Institute of Neuroscience and Mental Health, Alzheimer's Australia (AA), National Ageing Research Institute (NARI), Austin Health, CogState Ltd., Hollywood Private Hospital, and Sir Charles Gairdner Hospital. The study also receives funding from the National Health and Medical Research Council (NHMRC), the Dementia Collaborative Research Centres program (DCRC2) and the McCusker Alzheimer's Research Foundation and Operational Infrastructure Support from the Government of Victoria.