Least-squares (LS) deconvolution of a series of overlapping cortical auditory evoked potentials: a simulation and experimental study
Fabrice Bardy, Bram Van Dun, Harvey Dillon, Robert Cowan
Journal of Neural Engineering | IOP PUBLISHING LTD | Published : 2014
OBJECTIVE: To evaluate the viability of disentangling a series of overlapping 'cortical auditory evoked potentials' (CAEPs) elicited by different stimuli using least-squares (LS) deconvolution, and to assess the adaptation of CAEPs for different stimulus onset-asynchronies (SOAs). APPROACH: Optimal aperiodic stimulus sequences were designed by controlling the condition number of matrices associated with the LS deconvolution technique. First, theoretical considerations of LS deconvolution were assessed in simulations in which multiple artificial overlapping responses were recovered. Second, biological CAEPs were recorded in response to continuously repeated stimulus trains containing six diff..View full abstract
This work was supported in part by: the HEARing CRC, established and supported under the Cooperative Research Centres Program, an Australian Government Initiative; the Oticon Foundation; and the Australian Department of Health. We sincerely thank all participants in this study.