Journal article

Cocaine use and risk of stroke: A systematic review

L Sordo, BI Indave, G Barrio, L Degenhardt, L de la Fuente, MJ Bravo

Drug and Alcohol Dependence | ELSEVIER IRELAND LTD | Published : 2014


BACKGROUND: Both cocaine use and strokes impact public health. Cocaine is a putative cause of strokes, but no systematic review of the scientific evidence has been published. METHODS: All relevant bibliographic-databases were searched until January 2014 for articles on the epidemiological association between cocaine use and strokes. Search strings were supervised by expert librarians. Three researchers independently reviewed studies for inclusion and data extraction following STROBE recommendations. Quality appraisal included study validity and bias. Both ischemic and hemorrhagic strokes were considered. RESULTS: Of 996 articles, 9 were selected: 7 case-control studies (CCS) and 2 cross-sect..

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Awarded by National Plan on Drugs (Spain)

Awarded by Instituto de Salud Carlos III

Awarded by Postdoctoral Sara Borrell

Awarded by Addictive Disorder Network (RTA, in Spanish)

Awarded by Australian National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

The literature search was funded by the National Plan on Drugs (Spain) Grant number 2011/059 and EPY-02009 (Instituto de Salud Carlos III). Writing of the paper was supported by Postdoctoral Sara Borrell Contract (CD10/00128) and by Addictive Disorder Network (RTA, in Spanish) number RD12/0028/0018. Gregorio Barrio is supported by the Addictive Disorder Network (RTA). Louisa Degenhardt is supported by an Australian National Health and Medical Research Council (NHMRC) Principal Research Fellowship (#1041742). The National Drug and Alcohol Research Centre at the University of NSW is supported by funding from the Australian Government under the Substance Misuse Prevention and Service Improvements Grants Fund. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.