Journal article
Brain injury and altered brain growth in preterm infants: Predictors and prognosis
H Kidokoro, PJ Anderson, LW Doyle, LJ Woodward, JJ Neil, TE Inder
Pediatrics | Published : 2014
Abstract
BACKGROUND: To define the nature and frequency of brain injury and brain growth impairment in very preterm (VPT) infants by using MRI at term-equivalent age and to relate these findings to perinatal risk factors and 2-year neurodevelopmental outcomes. METHODS: MRI scans at term-equivalent age from 3 VPT cohorts (n = 325) were reviewed. The severity of brain injury, including periventricular leukomalacia and intraventricular and cerebellar hemorrhage, was graded. Brain growth was assessed by using measures of biparietal width (BPW) and interhemispheric distance. Neurodevelopmental outcome at age 2 years was assessed across all cohorts (n = 297) by using the Bayley Scales of Infant Development..
View full abstractGrants
Awarded by National Institute of Child Health and Development
Awarded by National Medical and Health Research Council of Australia
Awarded by Victorian Government's Operational Infrastructure Support Program, Neurologic Foundation of New Zealand
Funding Acknowledgements
All phases of this study were supported by National Institute of Child Health and Development (R01 HD057098, 1P0HD062171); the National Medical and Health Research Council of Australia (project grants 237117 and 491209; senior research fellowship 628371 to Dr Anderson); the Victorian Government's Operational Infrastructure Support Program, Neurologic Foundation of New Zealand (0012/PG); and the Doris Duke Charitable Foundation.