Journal article

A global consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease

KB Gecse, W Bemelman, MA Kamm, J Stoker, R Khanna, SC Ng, J Panés, G Van Assche, Z Liu, A Hart, BG Levesque, G D'Haens

Gut | Published : 2014

Abstract

Objective: To develop a consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease (pCD), based on best available evidence. Methods: Based on a systematic literature review, statements were formed, discussed and approved in multiple rounds by the 20 working group participants. Consensus was defined as at least 80% agreement among voters. Evidence was assessed using the modified GRADE (Grading of Recommendations Assessment, Development, and Evaluation) criteria. Results: Highest diagnostic accuracy can only be established if a combination of modalities is used. Drainage of sepsis is always first line therapy before initiating immunosuppr..

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University of Melbourne Researchers