Journal article

Impact of primary tumor volume on local control after definitive radiotherapy for head and neck cancer

William M Mendenhall, Anthony A Mancuso, Primoz Strojan, Jonathan J Beitler, Carlos Suarez, Tsair-Fwu Lee, Johannes A Langendijk, June Corry, Avraham Eisbruch, Alessandra Rinaldo, Alfio Ferlito

Head & Neck | WILEY-BLACKWELL | Published : 2014

Abstract

BACKGROUND: The impact of primary tumor volume (pTV) on local control after definitive radiotherapy (RT) for head and neck squamous cell carcinoma (HNSCC) is unclear. METHODS: Pertinent literature was reviewed to address the impact of pTV on local control after definitive RT for HNSCC. RESULTS: Reproducibility of pTV calculations is probably influenced by interobserver variability and may be reduced by relying on experienced observers. The impact of pTV on local control after definitive RT is probably influenced by primary site. A relatively limited impact of pTV on local control after RT for oropharyngeal squamous cell carcinomas (SCCs) might be attributable to human papillomavirus (HPV) po..

View full abstract

University of Melbourne Researchers