Journal article
Magnetic resonance post-contrast T1 mapping in the human atrium: Validation and impact on clinical outcome after catheter ablation for atrial fibrillation
LH Ling, AJA McLellan, AJ Taylor, LM Iles, AH Ellims, S Kumar, A Teh, G Lee, MCG Wong, S Azzopardi, MA Sellenger, JB Morton, JM Kalman, PM Kistler
Heart Rhythm | ELSEVIER SCIENCE INC | Published : 2014
Abstract
Background The impact of diffuse atrial fibrosis detected by T1 mapping on the clinical outcome after atrial fibrillation (AF) ablation is unknown. Objective This study aimed to validate and assess the impact of post-contrast cardiac magnetic resonance (CMR) imaging atrial T1 mapping on the clinical outcome after catheter ablation for AF. Methods CMR imaging was performed in 3 groups by using a clinical 1.5-T scanner: controls, patients with paroxysmal AF, and patients with persistent AF. A T1 mapping sequence was used to calculate the post-contrast T1 relaxation time (T1 time) at the interatrial septum as an index of diffuse atrial fibrosis. A subset underwent left atrial endocardial bipola..
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Funding Acknowledgements
This work was supported in part by the Victorian Government's Operational Infrastructure Funding. Dr Ling and Dr Wong are supported by an Australian National Heart Foundation Postgraduate Scholarship. Dr McLellan, Dr Ellims, and Dr Kumar are each supported by a cofunded National Health and Medical Research Council (NHMRC)/National Heart Foundation Postgraduate Scholarships. Dr Iles and Dr Lee are each supported by an Australian NHMRC Postgraduate Research Scholarship. Dr Taylor is supported by an NHMRC project grant. Dr Kistler is supported by a practitioner fellowship from the NHMRC.