Combination phentermine and topiramate for weight maintenance: The first Australian experience

Abstract

Objective: To investigate the safety, tolerability and efficacy of combination phentermine and topiramate therapy for maintenance of weight loss. Design, setting and patients: Retrospective audit of patients attending the Austin Health Weight Control Clinic who were dispensed phentermine-topiramate between 22 January 2010 and 16 July 2012 and after reaching a target weight by following a very low energy diet (VLED). Data collection continued until July 2013. Main outcome measures: Number of patients who ceased pharmacotherapy; duration of use of pharmacotherapy; types and numbers of adverse eff ects; and mean weight and blood pressure measurements at the initial visit, the end of the VLED an..