Novel concepts in the epidemiology, diagnosis and prevention of childhood tuberculosis
Nicole Ritz, Nigel Curtis
Swiss Medical Weekly | E M H SWISS MEDICAL PUBLISHERS LTD | Published : 2014
Tuberculosis (TB) is one of the oldest diseases known to mankind, yet it is the second leading cause of death from an infection worldwide today. In the absence of epidemiological data, TB in children was not considered significant and research efforts did not prioritise this group. More recently, there has been renewed interest in childhood TB, leading to improved understanding of the fundamental differences between children and adults in relation to both TB infection and disease. Children with TB infection have a high risk of rapid progression to disease which leads to challenges in diagnosis but also offers the opportunity to investigate biomarkers for infection, progression and protection..View full abstract
NR is supported by a career advancement grant from the University of Basel and the Rozalia foundation. No other potential conflict of interest relevant to this article was reported.