Journal article

Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P-falciparum and P-vivax

Brad E Sleebs, Michelle Gazdik, Matthew T O'Neill, Pravin Rajasekaran, Sash Lopaticki, Kurt Lackovic, Kym Lowes, Brian J Smith, Alan F Cowman, Justin A Boddey

Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2014


Awarded by National Health and Medical Research Council of Australia

Awarded by Human Frontiers Science Program

Awarded by Ramaciotti Foundation

Awarded by CASS Foundation Science and Medicine

Funding Acknowledgements

This work was funded by the National Health and Medical Research Council of Australia (project grant 1010326 to JAB.), the Human Frontiers Science Program (RGY0073/2012 to JAB.), the Ramaciotti Foundation (establishment grant 3197/2010 to JAB.), a CASS Foundation Science and Medicine grant (SM.12.4348 to JAB.), the Australian Cancer Research Foundation, and a Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS. We thank the University of Melbourne for the provision of a postgraduate scholarship awarded to M.G. A.F.C. is a Howard Hughes International Scholar and an Australia Fellow of the NHMRC. JAB. is a QEII Fellow of the Australian Research Council. We thank Dr Guillaume Lessene and Prof. David Huang for their helpful discussions.