MHC Class II Transactivator Is an In Vivo Regulator of Osteoclast Differentiation and Bone Homeostasis Co-opted From Adaptive Immunity
Elisa Benasciutti, Elisabetta Mariani, Laura Oliva, Maria Scolari, Egon Perilli, Emmanuele Barras, Enrico Milan, Ugo Orfanelli, Nicola L Fazzalari, Lara Campana, Annalisa Capobianco, Luc Otten, Francesca Particelli, Hans Acha-Orbea, Fabio Baruffaldi, Roberta Faccio, Roberto Sitia, Walter Reith, Simone Cenci
Journal of Bone and Mineral Research | WILEY | Published : 2014
Awarded by Ministero della Salute, Giovani Ricercatori
Awarded by Italian Association for Cancer Research
This study was supported by research grants to SC (European Calcified Tissue Society 2009 Career Establishment Award; Ministero della Salute, Giovani Ricercatori 2008-1143560 and 2009-1607545; Multiple Myeloma Research Foundation, 2010 Senior Research Award; and the Italian Association for Cancer Research, Special Program Molecular Clinical Oncology 5 per mille 9965). Work in WR's lab was supported by the Swiss National Science Foundation, the National Center of Competence in Research on Neural Plasticity and Repair (NCCR-NEURO), the Swiss Multiple Sclerosis Society, and the Geneva Cancer League. We are indebted to M Ascagni, M Baleani, C Covino, C Cucchi, A Del Fattore, S Dell'Oro, C Fersini, D Finke, F Grassi, N Lo Iacono, R Pacifici, MC Panzeri, N Pengo, P Podini, M Rocchi, P Rovere-Querini, N Rucci, C Sobacchi, S Takeshita, A Teti, A Villa, K Weilbaecher, and A Zallone for reagents and scientific advice. We are thankful to R Brambati, A Fella, and F Loro for technical and administrative assistance.