Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

Kally Yuen; Susy M Harrigan; Andrew J Mackinnon; Meredith G Harris; Hok Pan Yuen; Lisa P Henry; Henry J Jackson; Helen Herrman; Patrick D McGorry

Journal article

Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

Kally Yuen, Susy M Harrigan, Andrew J Mackinnon, Meredith G Harris, Hok Pan Yuen, Lisa P Henry, Henry J Jackson, Helen Herrman, Patrick D McGorry

SCHIZOPHRENIA RESEARCH | ELSEVIER SCIENCE BV | Published : 2014

DOI: 10.1016/j.schres.2014.07.042

Abstract

OBJECTIVE: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to identify baseline predictors of mortality. METHOD: Mortality outcomes in 723 young people presenting to an early psychosis service were prospectively ascertained up to 20 years. Predictors of all-cause and unnatural death were investigated using survival techniques. RESULTS: Forty-nine participants died by study end. Most deaths (n=41) occurred within 10 years of service entry. All-cause mortality was 5.5% at 10 years, rising to 8.0% after 20 years. Unnatural death rates at 10 and 20 years were 5.0% and 5.9%, respectively. Three risk factors consistently predicte..

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University of Melbourne Researchers

Hok Yuen Author Centre for Youth Mental Health

Kally Yuen Author Australian Mathematical Sciences Institute

Susy Harrigan Author Melbourne School of Population and Global Health

Helen Herrman Author Centre for Youth Mental Health

Patrick McGorry Author Centre for Youth Mental Health

Related Projects (1)

EMERGING SEVERE MENTAL ILLNESS IN YOUNG PEOPLE

Mental disorders, such as psychotic and severe mood disorders, are the largest cause of disability in Australia. However, there is still lit..

Grants

Awarded by Victorian Health Promotion Foundation Victoria, Australia

Awarded by Australian National Health and Medical Research Council Canberra, Australian Capital Territory, Australia

Funding Acknowledgements

This research was supported by the Victorian Health Promotion Foundation Victoria, Australia (grant number 91-0084C); the Australian National Health and Medical Research Council Canberra, Australian Capital Territory, Australia (grant number 350241); and the Colonial Foundation, Victoria, Australia. Funding sources played no role in the execution and analysis of the study or preparation of the manuscript.