Journal article

Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

Kally Yuen, Susy M Harrigan, Andrew J Mackinnon, Meredith G Harris, Hok Pan Yuen, Lisa P Henry, Henry J Jackson, Helen Herrman, Patrick D McGorry

SCHIZOPHRENIA RESEARCH | ELSEVIER SCIENCE BV | Published : 2014

Abstract

OBJECTIVE: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to identify baseline predictors of mortality. METHOD: Mortality outcomes in 723 young people presenting to an early psychosis service were prospectively ascertained up to 20 years. Predictors of all-cause and unnatural death were investigated using survival techniques. RESULTS: Forty-nine participants died by study end. Most deaths (n=41) occurred within 10 years of service entry. All-cause mortality was 5.5% at 10 years, rising to 8.0% after 20 years. Unnatural death rates at 10 and 20 years were 5.0% and 5.9%, respectively. Three risk factors consistently predicte..

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Grants

Awarded by Victorian Health Promotion Foundation Victoria, Australia


Awarded by Australian National Health and Medical Research Council Canberra, Australian Capital Territory, Australia


Funding Acknowledgements

This research was supported by the Victorian Health Promotion Foundation Victoria, Australia (grant number 91-0084C); the Australian National Health and Medical Research Council Canberra, Australian Capital Territory, Australia (grant number 350241); and the Colonial Foundation, Victoria, Australia. Funding sources played no role in the execution and analysis of the study or preparation of the manuscript.