Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

K Yuen; SM Harrigan; AJ Mackinnon; MG Harris; HP Yuen; LP Henry; HJ Jackson; H Herrman; PD McGorry

Journal article

Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

K Yuen, SM Harrigan, AJ Mackinnon, MG Harris, HP Yuen, LP Henry, HJ Jackson, H Herrman, PD McGorry

Schizophrenia Research | ELSEVIER SCIENCE BV | Published : 2014

DOI: 10.1016/j.schres.2014.07.042

Abstract

Objective: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to identify baseline predictors of mortality. Method: Mortality outcomes in 723 young people presenting to an early psychosis service were prospectively ascertained up to 20. years. Predictors of all-cause and unnatural death were investigated using survival techniques. Results: Forty-nine participants died by study end. Most deaths (n. =. 41) occurred within 10. years of service entry. All-cause mortality was 5.5% at 10. years, rising to 8.0% after 20. years. Unnatural death rates at 10 and 20. years were 5.0% and 5.9%, respectively. Three risk factors consistently..

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University of Melbourne Researchers

Kally Yuen Author

Susy Harrigan Author

Andrew MacKinnon Author

Hok Yuen Author

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Grants

Awarded by Eli Lilly and Company

Funding Acknowledgements

This research was supported by the Victorian Health Promotion Foundation Victoria, Australia (grant number 91-0084C); the Australian National Health and Medical Research Council Canberra, Australian Capital Territory, Australia (grant number 350241); and the Colonial Foundation, Victoria, Australia. Funding sources played no role in the execution and analysis of the study or preparation of the manuscript.