Journal article

Factors affecting perceptual thresholds in a suprachoroidal retinal prosthesis

MN Shivdasani, NC Sinclair, PN Dimitrov, M Varsamidis, LN Ayton, CD Luu, T Perera, HJ McDermott, PJ Blamey

Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2014

Abstract

PURPOSE. The suprachoroidal location for a retinal prosthesis provides advantages over other locations in terms of a simplified surgical procedure and a potentially more stable electrode–neural interface. The aim of this study was to assess the factors affecting perceptual thresholds, and to optimize stimulus parameters to achieve the lowest thresholds in patients implanted with a suprachoroidal retinal prosthesis.METHODS. Three patients with profound vision loss from retinitis pigmentosa were implanted with a suprachoroidal array. Perceptual thresholds measured on individual electrodes were analyzed as a function of stimulus (return configuration, pulse polarity, pulse width, interphase gap..

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Grants

Awarded by National Health and Medical Research Council Centre for Clinical Research


Funding Acknowledgements

Supported by the Australian Research Council through its Special Research Initiative in Bionic Vision Science and Technology awarded to Bionic Vision Australia and by the Bertalli Family Foundation to the Bionics Institute. The Bionics Institute and the Centre for Eye Research Australia (CERA) acknowledge the support received from the Victorian Government through its Operational Infrastructure Program. CERA is also supported by National Health and Medical Research Council Centre for Clinical Research Excellence Award 529923.