Journal article

Social cognition in patients following surgery to the prefrontal cortex

Lisanne Michelle Jenkins, David Gordon Andrewes, Christian Luke Nicholas, Katharine Jann Drummond, Bradford Armstrong Moffat, Pramit Phal, Patricia Desmond, Roy Peter Caspar Kessels

Psychiatry Research | ELSEVIER IRELAND LTD | Published : 2014

Abstract

Impaired social cognition, including emotion recognition, may explain dysfunctional emotional and social behaviour in patients with lesions to the ventromedial prefrontal cortex (VMPFC). However, the VMPFC is a large, poorly defined area that can be sub-divided into orbital and medial sectors. We sought to investigate social cognition in patients with discrete, surgically circumscribed prefrontal lesions. Twenty-seven patients between 1 and 12 months post-neurosurgery were divided into groups based on Brodmann areas resected, determined by post-surgical magnetic resonance imaging. We hypothesised that patients with lesions to the VMPFC (n=5), anterior cingulate cortex (n=4), orbitofrontal co..

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