Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal
Ihaia T Hosken, Steven W Sutton, Craig M Smith, Andrew L Gundlach
Behavioural Brain Research | ELSEVIER SCIENCE BV | Published : 2015
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Awarded by National Health and Medical Research Council of Australia
This research was supported by National Health and Medical Research Council of Australia project grants 509246, 1005985 and 1024885 (A.L.G.) and postgraduate scholarship 1017408 (I.T.H.), grants from the Pratt and Besen Family Foundations (A.L.G.), a Brain & Behavior Research Foundation (USA) NARSAD Independent Investigator Award (A.L.G.), and the Victorian Government Operational Infrastructure Support Programme. The authors thank Dr Timothy Lovenberg (Neuroscience Drug Discovery, Janssen Pharmaceutical Companies of Johnson & Johnson, San Diego, USA) for commissioning the production of the Rxfp3 KO strain and providing The Florey Institute of Neuroscience and Mental Health with an original breeding colony; and Simon Miller and Brett Purcell (The Florey Institute of Neuroscience and Mental Health) for assistance with automated running wheel production and maintenance, and assistance with behavioural equipment and analysis, respectively.