Journal article

Laparoscopic Repair of Very Large Hiatus Hernia With Sutures Versus Absorbable Mesh Versus Nonabsorbable Mesh A Randomized Controlled Trial

David I Watson, Sarah K Thompson, Peter G Devitt, Lorelle Smith, Simon D Woods, Ahmad Aly, Susan Gan, Philip A Game, Glyn G Jamieson

Annals of Surgery | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015


OBJECTIVE: Determine whether absorbable or nonabsorbable mesh in repair of large hiatus hernias reduces the risk of recurrence, compared with suture repair. BACKGROUND: Repair of large hiatus hernia is associated with radiological recurrence rates of up to 30%, and to improve outcomes mesh repair has been recommended. Previous trials have shown less short-term recurrence with mesh, but adverse outcomes limit mesh use. METHODS: Multicentre prospective double blind randomized controlled trial of 3 methods of repair: sutures versus absorbable mesh versus nonabsorbable mesh. Primary outcome-hernia recurrence assessed by barium meal radiology and endoscopy at 6 months. Secondary outcomes-clinical..

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University of Melbourne Researchers


Awarded by National Health and Medical Research Council (NHMRC) of Australia

Funding Acknowledgements

This randomized trial was supported by Research Project Grants from the National Health and Medical Research Council (NHMRC) of Australia (Grant numbers 375111 and 1022722). This trial is registered with the Australia and New Zealand Clinical Trials Registry ACTRN12605000725662. The authors declare no conflicts of interest.