Alpha-synuclein oligomers and fibrils originate in two distinct conformer pools: a small angle X-ray scattering and ensemble optimisation modelling study
Cyril C Curtain, Nigel M Kirby, Haydyn DT Mertens, Kevin J Barnham, Robert B Knott, Colin L Masters, Roberto Cappai, Agata Rekas, Vijaya B Kenche, Timothy Ryan
MOLECULAR BIOSYSTEMS | ROYAL SOC CHEMISTRY | Published : 2015
The authors wish to acknowledge the support of the Australian Synchrotron and the Victorian Government Operational Infrastructure Support Program. TMR is supported by the Australian Alzheimer's disease foundation. CLM and KJB are consultants for Prana Biotechnology Pty Ltd. CLM, KJB and RC are the principal investigators on an Australian National Health and Medical Research Council program grant.