High Order W02-Reactive Stable Oligomers of Amyloid-beta are Produced in vivo and in vitro via Dialysis and Filtration of Synthetic Amyloid-beta Monomer

Elysia Robb; Keyla Perez; Lin W Hung; Colin L Masters; Kevin J Barnham; Robert A Cherny; Ashley I Bush; Paul A Adlard; David I Finkelstein

Journal article

High Order W02-Reactive Stable Oligomers of Amyloid-beta are Produced in vivo and in vitro via Dialysis and Filtration of Synthetic Amyloid-beta Monomer

Elysia Robb, Keyla Perez, Lin W Hung, Colin L Masters, Kevin J Barnham, Robert A Cherny, Ashley I Bush, Paul A Adlard, David I Finkelstein

Journal of Alzheimer's Disease | IOS PRESS | Published : 2015

DOI: 10.3233/JAD-132024

University of Melbourne Researchers

Kevin Barnham Author Florey Department of Neuroscience and Mental Health

Ashley Bush Author Florey Department of Neuroscience and Mental Health

Colin Masters Author Florey Department of Neuroscience and Mental Health

David Finkelstein Author Florey Department of Neuroscience and Mental Health

Related Projects (4)

Developing A Novel Therapy For Parkinson'S Disease

By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a large proportion (60-70%) of the cells in a speci..

Iron Export Protein Failure In Parkinsonism And Dementia

We recently discovered a novel relationship between the Alzheimer’s amyloid precursor protein (APP) and tau, and that both proteins play a r..

Identifying The Mechanisms Of Action Of A Novel 8-Hydroxy Quinazolinone In Models Of Parkinson'S Disease

By the time symptoms of Parkinson's disease (PD) appear, 60-70% of the cells in a crucial part of the brain called the substantia nigra have..

Translational Therapeutics And Diagnostics For Alzheimer'S Disease

nan

Grants

Funding Acknowledgements

Australian National Health and Medical Research Council. PAA and DIF are supported by funds from the NH&MRC, the ARC, the Alzheimer's Association (USA), and the Joan and Peter Clemenger Trust. The Florey Institute of Neuroscience and Mental Health acknowledge the strong support from the Victorian Government and in particular the funding from the Operational Infrastructure Support Grant.