Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)
K Newton, NM Jorgensen, AJ Wallace, DD Buchanan, F Lalloo, RFT McMahon, J Hill, DG Evans
Journal of Medical Genetics | BMJ PUBLISHING GROUP | Published : 2014
Keeling C and Griffiths-Davies L (Department of Histopathology, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust) for conducting immunohistochemistry. Newton K, Jorgensen NM, Lalloo, F, Hill J, and Evans DG are supported, by Manchester NIHR BRC. Biospecimens were provided by The Jeremy Jass Memorial Pathology Bank, Australasian Colorectal Cancer Family Registry (U01 CA097735).