Journal article
Decreased retinal capillary flow is not a mediator of the protective myopia-diabetic retinopathy relationship
REYK Man, MBA Sasongko, J Xie, WJ Best, JE Noonan, TCHS Lo, JJI Wang, CD Luu, EL Lamoureux
Investigative Ophthalmology Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2014
Abstract
PURPOSE: The mechanisms supporting the protective relationship between a longer axial length (AL) and a decreased risk of diabetic retinopathy (DR) remain unclear. Previous studies have demonstrated reduced retinal blood flow in axial myopia, and it has been suggested that the compromised retinal capillaries in diabetes are less likely to leak and rupture as a result of this decreased flow. In this study, we therefore investigated if reduced retinal capillary flow (RCF) is a potential mechanism underpinning this protective relationship.METHODS: Retinal capillary flow was assessed using the Heidelberg Retinal Flowmeter in 150 eyes of 85 patients with diabetes aged 18+ years from the Royal Vic..
View full abstractGrants
Awarded by Australian Research Council Linkage Grant
Awarded by National Health and Medical Research Council Centre for Clinical Research Excellence, Translational Clinical Research in Major Eye Diseases
Funding Acknowledgements
Supported by Australian Research Council Linkage Grant LP0884108 and by the National Health and Medical Research Council Centre for Clinical Research Excellence 52992, Translational Clinical Research in Major Eye Diseases. The Centre for Eye Research Australia receives operational infrastructure support from the Victorian Government. The authors alone are responsible for the content and writing of the paper.