Journal article

CLINICAL SIGNS ASSOCIATED WITH TRIPLE ANTIGEN (DTP) VACCINATION IN INFANTS

G HARRIS, T NOLAN, L HARTMAN

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | BLACKWELL SCIENCE PUBL AUSTR | Published : 1995

Abstract

OBJECTIVE: The perceived reactogenicity of pertussis-containing vaccines is of considerable public health importance. The purpose of this study was to establish prospectively the incidence of systemic and local clinical signs associated with the first three doses of the diphtheria-tetanus-pertussis vaccine (DTP) currently used in Australia. In addition, in order to determine whether variability in reporting of such phenomena might be associated with variation in DTP batches, infant behaviour was studied with three batches for the first of the three DTP vaccinations. METHODOLOGY: Double blind, randomized controlled trial. There were 591 eligible infants who were recruited sequentially from ce..

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University of Melbourne Researchers