CD3(bright) signals on gamma delta T cells identify IL-17A-producing V gamma 6V delta 1( ) T cells

C Paget; MT Chow; NA Gherardin; PA Beavis; AP Uldrich; H Duret; M Hassane; F Souza-Fonseca-Guimaraes; DA Mogilenko; D Staumont-Salle; NK Escalante; GR Hill; P Neeson; DS Ritchie; D Dombrowicz; T Mallevaey; F Trottein; GT Belz; DI Godfrey; MJ Smyth

Journal article

CD3(bright) signals on gamma delta T cells identify IL-17A-producing V gamma 6V delta 1( ) T cells

C Paget, MT Chow, NA Gherardin, PA Beavis, AP Uldrich, H Duret, M Hassane, F Souza-Fonseca-Guimaraes, DA Mogilenko, D Staumont-Salle, NK Escalante, GR Hill, P Neeson, DS Ritchie, D Dombrowicz, T Mallevaey, F Trottein, GT Belz, DI Godfrey, MJ Smyth

Immunology and Cell Biology | NATURE PUBLISHING GROUP | Published : 2015

DOI: 10.1038/icb.2014.94

University of Melbourne Researchers

Dale Godfrey Author Microbiology and Immunology

Gabrielle Belz Author Medical Biology (W.E.H.I.)

Nicholas Gherardin Author Microbiology and Immunology

Adam Uldrich Author Microbiology and Immunology

Paul Neeson Author The Sir Peter MacCallum Department of Oncology

Related Projects (3)

Research Fellowship

Professor Godfrey is an immunologist with a long standing history as a pioneer in the study of a specialised type of white blood cell, known..

2007 Program Grant - (Immune Regulation, Effector Function And Human Immunotherapy)

The immune system plays an important role in protecting the host from viral and bacterial infections, and inhibits cancer onset and progress..

2007 Program Grant - (Immune Regulation, Effector Function And Human Immunotherapy)

The immune system plays an important role in protecting the host from viral and bacterial infections, and inhibits cancer onset and progress..

Grants

Awarded by NHMRC

Awarded by US Department of Defense

Awarded by National Health and Medical Research Council of Australia (NHMRC) Australia Fellowship

Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC Senior Principal Research Fellowship

Awarded by Agence Nationale de la Recherche

Funding Acknowledgements

We thank Josette Fontaine, Shin-Foong Ngiow, Deborah Knight, Sebastien Fleury, Julien Wartelle and Kim Steegh for technical assistance. We thank Qerime Mundrea, Ben Venville, Jessica May, Joanne Sutton and Liam Town for maintaining and caring for the mice. We also thank the Peter MacCallum flow cytometry core facility for technical assistance. This work was supported by an NHMRC Program Grant (454569 and 1013367). CP was supported by a postdoctoral fellowship from the US Department of Defense (W81XWH-11-1-0585) and INSERM. MJS and FSFG were supported by a National Health and Medical Research Council of Australia (NHMRC) Australia Fellowship and Program Grant (1013367). MTC was supported by a Cancer Research Institute PhD scholarship. GTB was supported by an ARC Future Fellowship. FT was supported by CNRS. PN was supported by a National Health and Medical Research Council of Australia (NHMRC) Program Grant (1013367). DIG was supported by an NHMRC Senior Principal Research Fellowship (1020770). NAG was supported by a Leukaemia Foundation of Australia postgraduate scholarship. TM is supported by research grants from the Canadian Institutes of Health Research and the Crohn and Colitis Foundation of Canada, as well as a Tier 2 Canada Research Chair. NKE is a recipient of a Vanier Canada Graduate Scholarship. DAM, DS-S and DD were supported by the Agence Nationale de la Recherche (ANR-10-LABX-46) and the 'Fondation de France'.