Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries: A systematic review

Abstract

Introduction: Forty per cent of global child deaths occur in the neonatal period. Low and middle income countries need effective and simple methods to improve hospital-based neonatal care. Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries. Aim: To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings. Method: A systematic search (1946-March 2014) was performed of Pubmed, Ovid MEDLINE, Web of Science, Google Scholar and the references of relevant articles. Articles meeting inclusion criteria (CPAP for ..