Journal article
The gut microbiome and diet in psychiatry: Focus on depression
S Dash, G Clarke, M Berk, FN Jacka
Current Opinion in Psychiatry | Published : 2015
Abstract
Purpose of review: With depressive disorders the leading source of disability globally, the identification of new targets for prevention and management is imperative. A rapidly emerging field of research suggests that the microbiome-gut-brain axis is of substantial relevance to mood and behaviour. Similarly, unhealthy diet has recently emerged as a significant correlate of and risk factor for depression. This review provides evidence for the gut microbiota as a key factor mediating the link between diet and depressive illness.Recent findings: The development of new technologies is affording a better understanding of how diet influences gut microbiota composition and activity and how this may..
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Funding Acknowledgements
M.B. is supported by an NHMRC Senior Principal Research Fellowship 1059660. The Alimentary Pharmabiotic Centre is a research centre funded by Science Foundation Ireland (SFI; grant number SFI/12/RC/2273). G.C. is supported by a NARSAD Young Investigator Grant from the Brain and Behavior Research Foundation (grant number 20771). F. J. is supported by Deakin University.