Journal article

Alcohol consumption for different periods in life, intake pattern over time and all-cause mortality

Harindra Jayasekara, Robert J MacInnis, Allison M Hodge, John L Hopper, Graham G Giles, Robin Room, Dallas R English



BACKGROUND: Conventionally, cohort studies have assessed the association between alcohol and all-cause mortality by using alcohol intake at enrolment. METHODS: In the Melbourne Collaborative Cohort Study, participants were asked about usual frequency and quantity of beverage-specific alcohol intake for 10-year periods starting at age 20 from which current, past and lifetime intakes were calculated. We used Cox regression to estimate hazard ratios for mortality for 39 577 participants of the Melbourne Collaborative Cohort Study aged 40-69 at baseline. RESULTS: After a mean follow-up of 15 years/person, we identified 4639 deaths. Associations between all-cause mortality and lifetime, current (..

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Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by grants from the National Health and Medical Research Council (grant numbers 209057, 251533, 396414) and the Australian Brewers Foundation. Cohort recruitment was funded by VicHealth and The Cancer Council Victoria. Further infrastructure support was provided by The Cancer Council Victoria. H.J. is the recipient of a postgraduate scholarship from the National Health and Medical Research Council (1017346). J.H. is a National Health and Medical Research Council Senior Principal Research Fellow. R.R.'s position is funded by the Victorian Department of Health and the Foundation for Alcohol Research and Education. No funding statements to declare for authors R.J.M., A.H., G.G.G. and D.R.E.