Journal article
Abnormalities in orbitofrontal cortex gyrification and mental health outcomes in adolescents born extremely preterm and/or at an extremely low birth weight
EP Ganella, A Burnett, J Cheong, D Thompson, G Roberts, S Wood, K Lee, J Duff, PJ Anderson, C Pantelis, LW Doyle, C Bartholomeusz
Human Brain Mapping | Published : 2015
DOI: 10.1002/hbm.22692
Abstract
Extremely preterm (EP, <28 weeks) and/or extremely low birth weight (ELBW, 37 completed weeks) and/or normal birth weight (>2500 g) adolescents were acquired, from which the OFC pattern of each hemisphere was classified as Type I, II, or III. Compared with controls, more EP/ELBW adolescents possessed a Type II in the left hemisphere (P=0.019). The EP/ELBW group had fewer IOS (P=0.024) and more POS (P=0.021) in the left hemisphere compared with controls. OFC pattern type was not associated with mental illness, however in terms of executive functioning, Type III in the left hemisphere was associated with better parent-reported metacognition scores overall (P=0.008) and better self-reported beh..
View full abstractGrants
Awarded by Australian National Health and Medical Research Council
Awarded by Centre of Clinical Research Excellence
Awarded by Early Career Fellowship
Awarded by Senior Research Fellowship
Awarded by Senior Principal Research Fellowship
Funding Acknowledgements
Contract grant sponsor: Australian National Health and Medical Research Council; Contract grant number: 491246 (to L.D., P.A., S.W., J.C., and G.R., as well as C Robertson, S Hope, and D Hacking); Contract grant sponsor: Centre of Clinical Research Excellence; Contract grant number: 546519; Contract grant sponsor: Early Career Fellowship; Contract grant number: 1053787 (to J.C.); Contract grant sponsor: Early Career Fellowship; Contract grant number: 1012236 (to D.T.); Contract grant sponsor: Senior Research Fellowship; Contract grant number: 628371 (to P.A., C.P.); Contract grant sponsor: Senior Principal Research Fellowship; Contract grant number: 628386; Contract grant sponsor: Victorian Government Operational Infrastructure Support Program.