Journal article

Mammographic density and risk of breast cancer in Korean women

Bo-Kyoung Kim, Yoon-Ho Choi, Tuong L Nguyen, Seok Jin Nam, Jeong Eon Lee, John L Hopper, Joohon Sung, Yun-Mi Song

European Journal of Cancer Prevention | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015

Abstract

We carried out this study to evaluate the association between mammographic density adjusted for age and BMI and early-onset breast cancer in Asian women. We recruited 213 Korean patients with breast cancer (45% diagnosed before the age of 50 years) and 630 controls matched for age, menopausal status, and examination date. The percentage and absolute size of dense areas on digital mammograms were measured using a computer-assisted thresholding technique (Cumulus). We carried out an analysis using the conditional logistic regression model with adjustment for covariates. An increase by 1 SD in age and BMI-adjusted absolute dense area and percentage dense area was associated with a 1.15-fold (95..

View full abstract

Grants

Awarded by Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT, and future Planning


Funding Acknowledgements

This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and future Planning (2011-0013545 and 2014R1A2A2A01002705).