Journal article

Increased risk of peanut allergy in infants of Asian-born parents compared to those of Australian-born parents

JJ Koplin, RL Peters, AL Ponsonby, LC Gurrin, D Hill, MLK Tang, SC Dharmage, KJ Allen

Allergy European Journal of Allergy and Clinical Immunology | Published : 2014

Abstract

Background: Asian infants appear to be over-represented among patients with clinical food allergy in Australia, but this has not been formally examined at the population level. Any difference in prevalence according to parental country of birth may be secondary to modifiable lifestyle factors. We aimed to quantify (i) differences in the prevalence of peanut allergy by parental country of birth and (ii) contribution of measured environmental exposures to these differences. Methods: The population-based HealthNuts study in Melbourne, Australia, screened 5276 infants (74% participation) with skin prick tests and sensitized infants underwent food challenge. Of these, 535 had a parent born in Eas..

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Grants

Funding Acknowledgements

This study was funded by the Australian National Health and Medical Research Council, the Ilhan Food Allergy Foundation, AnaphylaxiStop, the Charles and Sylvia Viertel Medical Research Foundation and the Victorian Government's Operational Infrastructure Support Program. We thank ALK Abello S. A. Madrid, Espana for supplying skin prick test reagents. KJA is a Viertel Senior Medical Research Fellow. RLP is an Australian Postgraduate Award scholar. LCG, A-LP, JJK and SCD hold National Health & Medical Research Council Awards.