Journal article
Arterial elasticity in obese adolescents with clinical features of insulin resistance
M Ho, PZ Benitez-Aguirre, KC Donaghue, P Mitchell, LA Baur, AJ Jenkins, ME Craig, CT Cowell, SP Garnett
Diabetes and Vascular Disease Research | SAGE PUBLICATIONS LTD | Published : 2015
Abstract
Results: SAEI and LAEI raw values were higher in the IR group than the controls, and these did not differ between the T1D and control groups. Weight and diastolic blood pressure (DBP) were significant predictors of SAEI. After adjustment for weight and DBP, SAEI decreased by 0.65 mL/mmHg 100 for each 1-year increase in age in the IR group. SAEI was not different across the groups after controlling for weight and DBP. Height was the strongest predictor of LAEI which remained higher in the IR group after controlling for height and blood pressure.Objective: To determine whether arterial elasticity differs between obese adolescents with clinical insulin resistance (IR), type 1 diabetes (T1D) and..
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Funding Acknowledgements
The RESIST study was funded by BUPA Foundation Australia Pty Limited (2008-2012), Diabetes Australia Research Trust (DART, 2008) and Heart Foundation, Australia (2009-2010). M.H. is supported by a National Health and Medical Research Council (NHMRC) Australian Dora Lush Postgraduate Research Scholarship. S.P.G. was supported by an Early Career Research Fellowship, Cancer Institute NSW (2011-2013). The remaining authors have no financial relationships relevant to this article to disclose.