Journal article
MRI grading versus histology: Predicting survival of world health organization grade II-IV astrocytomas
A Lasocki, A Tsui, MA Tacey, KJ Drummond, KM Field, F Gaillard
American Journal of Neuroradiology | Published : 2015
DOI: 10.3174/ajnr.A4077
Abstract
Background and Purpose: Histologic grading of intracranial astrocytomas is affected by sampling error and substantial inter- and intraobserver variability. We proposed that incorporating MR imaging into grading will predict patient survival more accurately than histopathology alone. Materials and Methods: Patients with a new diagnosis of World Health Organization grades II-IV astrocytoma or mixed oligoastrocytoma diagnosed between September 2007 and December 2010 were identified. Two hundred forty-five patients met the inclusion criteria. Preoperative MRIs were independently reviewed by 2 readers blinded to the histologic grade, and an MR imaging grade was given. The MR imaging and histopath..
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Funding Acknowledgements
Arian Lasocki-RELATED: Support for Travel to Meetings for the Study or Other Purposes: Radiology Resources (prize awarded by the Royal Australian and New Zealand College of Radiologists). Kathryn M. Field-UNRELATED: Payment for Lectures (including service on Speakers Bureaus): Roche; Travel/Accommodations/Meeting Expenses Unrelated to Activities Listed: Merck Sharp and Dohme. Frank Gaillard-UNRELATED: Consultancy: Medtronic, Comments: educational talks about MRI in the context of MRI-safe pacemakers and neurostimulators; Employment Radiopaedia.org, Comments: Founder, Editor, CEO of Radiopaedia.org, an online collaborative radiology resource, www.radiopaedia.org.