Journal article
Favorable Outcomes from Allogeneic and Autologous Stem Cell Transplantation for Patients with Transformed Nonfollicular Indolent Lymphoma
D Villa, A George, JF Seymour, CL Toze, M Crump, C Lee, R Buckstein, DA Stewart, D MacDonald, R Foley, A Xenocostas, M Sabloff, N Chua, F Couture, JF Larouche, S Cohen, KJ Savage, JM Connors, T Panzarella, DA Carney Show all
Biology of Blood and Marrow Transplantation | Published : 2014
Abstract
The role of allogeneic (allo-) and autologous stem cell transplantation (auto-SCT) in the management of patients with transformed indolent nonfollicular non-Hodgkin lymphoma is unknown. This is a multicenter, retrospective cohort study of patients with biopsy-proven indolent B cell nonfollicular non-Hodgkin lymphoma and simultaneous or subsequent biopsy-proven aggressive histology transformation who were treated with allo-SCT or auto-SCT between 1996 and 2013. All patients received myeloablative conditioning regimens. Outcomes were compared with a cohort of 246 patients with transformed follicular lymphoma who also underwent allo-SCT (n = 47) or auto-SCT (n = 199) across the same institution..
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Funding Acknowledgements
Supported by a 2010 Canadian Blood and Marrow Transplant Group Small Budget Research Grant.